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Three steps to mastitis treatment success

November 14, 2018
POSTED BY: Juan Rodrigo Pedraza | DVM | Managing Veterinarian | Zoetis

Mastitis is too costly to mess around with a treatment that may not provide a complete cure. If the tube you are using doesn’t clear up the clinical signs of infection AND any bacteria remains in the udder, you could face mastitis infection relapse and additional costs.

The costs associated with an incomplete cure and relapses can add up — chronically infected cows, expensive re-treatments and the potential spread of mastitis-causing pathogens. The ultimate effects are overall reduced production and increased expenses. On the other hand, a complete mastitis cure can mean more milk in the tank. Cows with complete mastitis cures gave 8.8 pounds more milk than cows not cured, according to a Cornell University study.1

For complete bacteriological cures and to prevent mastitis relapse, make this your treatment mantra: A clinical mastitis cure may not equal a bacteriological cure. Stopping treatment because clinical symptoms clear up doesn’t guarantee a complete cure. Unfortunately, a clinical cure, when milk returns to normal, may not be the same as a bacteriological cure and may not equal treatment success — mastitis-causing pathogens may remain in the udder. 

Help to attack mastitis-causing pathogens and achieve successful treatment outcomes the first time by applying these three tips:

  • Know her health history: Not all cows are good candidates for intramammary therapy, make your decision based on the cow’s treatment history, length of infection, age, health status and lactation stage. It’s also important to identify the pathogen causing the infection by culturing milk samples from infected quarters. With this information, your veterinarian can prescribe the appropriate mastitis treatment and protocol.
  • Tailor treatment: For those difficult mastitis pathogens, flexible mastitis therapy that’s on-label can sometimes be necessary to achieve a bacteriological cure and help reduce the chance of relapse. The option of flexible label mastitis therapy helps tailor treatment duration to the individual case for mastitis when extra days of therapy are needed. SPECTRAMAST® LC (ceftiofur hydrochloride) Sterile Suspension is approved for additional treatments and provides the flexibility to continue once-daily treatment for up to eight consecutive days for more stubborn mastitis cases*.
  • Monitor treatment success to make sure you’re seeing high bacteriological cure rates, lower relapse rates and lower bulk tank somatic cell counts. Good records and monitoring are the only ways to know whether the treatment is working.

To learn more about achieving a complete, or bacteriological, mastitis cure, flexible label mastitis therapy with SPECTRAMAST LC and how a high somatic cell count can lower your profitability, contact your Zoetis representative.

IMPORTANT DIAGNOSTIC INFORMATION: SPECTRAMAST LC is intended for use in lactating dairy cattle only with the specified, labeled pathogens. To assure responsible antimicrobial drug use, it is expected that subclinical mastitis will be diagnosed using a positive culture, or other pathogen-specific test, in addition to any other, appropriate veterinary medical evaluation prior to treatment.

IMPORTANT SAFETY INFORMATION: People with known hypersensitivity to penicillin or cephalosporins should avoid exposure to SPECTRAMAST LC. Product requires a 72-hour milk discard period and a 2-day pre-slaughter withdrawal period following the last treatment. Use of this product in a manner other than indicated on the label, or failure to adhere to proper milk discard period, will result in violative residues. See full Prescribing Information.

*SPECTRAMAST LC (ceftiofur intramammary suspension) Sterile Suspension is indicated for use in lactating dairy cattle for (1) the treatment of clinical mastitis associated with coagulase-negative staphylococci, Streptococcus dysgalactiae, and Escherichia coli and (2) the treatment of diagnosed subclinical mastitis associated with coagulase-negative staphylococci and Streptococcus dysgalactiae.

1 Schukken YH, Bennett GJ, Zurakowski MJ, et al. Randomized clinical trial to evaluate the efficacy of a 5-day ceftiofur hydrochloride intramammary treatment on nonsevere Gram-negative clinical mastitis. J Dairy Sci. 2011;94(12):6203-6215.




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