Here's Why It's Important to Control Mastitis During the Dry Period

Dry cow mastitis therapy is necessary to treat existing infections and to prevent new infections in the early dry period. The figure below illustrates that new mastitis infections peak at dry-off and in early-lactation.

These research studies document mastitis cases during the dry period:

  • 60% of all gram-negative intramammary mastitis infections occur during the dry period (Todhunter et al., Am. J. Vet. Res. 52:184, 1991)


  • In a UK study, more than 50% of all clinical mastitis due to Enterobacteriacae arose from quarters that had previously become infected during the dry period (Bradley et al., Proceedings of the National Mastitis Council, 1999)


  • Untreated intramammary infections can remain quiescent in the udder until calving, causing mastitis in early lactation (McDonald et al., Am. J. Vet. Res. 42:229, 1981)

Clinical mastitis is most common in the first 100 days after calving. Severe cases cause decreased milk yield, poor reproduction, loss of quarters and/or death of the animal. Other possible effects of severe mastitis are endotoxemia and fever, which may reduce the cow's appetite and lead to negative energy balance.

A University of Tennessee study conducted by Schrick et al. confirmed that cows with subclinical mastitis suffered reproductive problems. The worst effects occurred in cows that were subclinically infected and then became clinical between first service and pregnancy. Clinically infected cows had 93.9 days to first service compared to 67.8 days for cows without mastitis; 196.0 days open vs. 85.4 days; and 4.3 services per conception vs. 1.6 services.

Mastitis prevention actions

  • Provide clean and dry housing. Clean, dry and comfortable housing is a must for both dry and lactating cows. Use the knee test to check bedding moisture daily. Stand at the back of a freestall or on a bedding pack and drop to your knees. Upon standing again, if your knees are damp or wet, the bedding should be changed.


  • Use proper dry-cow mastitis treatment and vaccinate with UPJOHN J-5 BACTERIN™ (Escherichia Coli Bacterin J-5 Strain) to minimize mastitis during the dry and transition periods. Data compiled for three lactations demonstrate consistent performance advantages over non-vaccinated herdmates.


Table 1 summarizes a multi-location trial starting with more than 400 cows. Vaccinated vs. control cows were evaluated over three lactations. The vaccinated cows averaged a 65 percent reduction in clinical coliform mastitis cases over the three years.

Table 1

Results of UC-Davis J-5 Trial #1
Vaccinated
Group*
Non-Vaccinated
Controls
Number of animals
246
240
% incidence of clinical
coliform mastitis
2.57
12.77
# culled due to clinical
coliform mastitis
0
4**
*Three doses of J-5 were delivered to 246 adult cattle.
**Three animals were culled due to chronic coliform mastitis,
and one because of post-coliform agalactia.

(Gonzales, R.N., J.S. Cullor, D.E. Jaster, T.G. Farver, R.B. Bushnell and M.N. Oliver, "Prevention of Clinical Coliform Mastitis in Dairy Cows by a Mutant Escherichia coli Vaccine," Canadian Journal of Veterinary Research, 1989;53:301-305)


UPJOHN J-5 BACTERIN Delivers Results

In a trial involving 486 cows, the vaccinated group showed an incidence of coliform mastitis of just 2.57 percent, compared to a 12.77 percent incidence for the non-vaccinated control group.

Table 2

Results of Tulare VMTRC J-5 Trial — Coliform Mastitis Incidence
Upjohn J-5
Placebo
% reduction by Upjohn J-5
Year 1

3.54%

7/198

11.06%

25/226

68%

Year 2

5.22%

6/115

13.38%

19/142

61%

Year 3
3.89%
11.32%
66%
(Borrell, C.L. et al, Abstract 12, 11th Annual Food Animal Discovery Research Conference, UNR, 1990)

Reducing the number of cows culled due to coliform mastitis is often overlooked when considering the numerous advantages of using UPJOHN J-5 BACTERIN.

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